From the East:  Take I-94 West to Detroit, exit I-75 South.  Take I-75 South and exit on Mack Avenue.  Turn right (west) on Mack Avenue.  Take Mack to Beaubien.  Make a right (north) on Beaubien.  Children's Hospital will be on your left hand side. From the West:  Take I-94 East to Detroit, exit I-75 South.  Take I-75 South and exit on Mack Avenue.  Turn right (west) on Mack Avenue.  Take Mack to Beaubien.  Make a right (north) on Beaubien.  Children's Hospital will be on your left hand side. From the South:Take I-75 North to Detroit, exit on Mack Avenue. Turn left (east) on Mack Avenue.  Take Mack to Beaubien.  Make a right (north) on Beaubien.  Children's Hospital will be on your left hand side. From the North:  Take I-75 South to Detroit, exit on Mack Avenue. Turn right (west) on Mack Avenue.  Take Mack to Beaubien.  Make a right (north) on Beaubien.  Children's Hospital will be on your left hand side. From the Northwest:  Take Lodge (10) Freeway South to Detroit, exit on Forest/Warren.  Make a U-turn over the freeway so that you will coming back North on the service drive.  Take the service drive to Warren and turn right (east).  Take Warren to St. Antoine and turn right (south).  St. Antoine turns into Beaubien, and Children's Hospital will be on your right hand side. From Detroit Metro Airport:  Take I-94 East to Detroit, exit I-75 South.  Take I-75 South and exit on Mack Avenue.  Turn right (west) on Mack Avenue.  Take Mack to Beaubien.  Make a right (north) on Beaubien.  Children's Hospital will be on your left hand side.